Precocious puberty
It is an early (before 8 years in girls and 9 years in boys) puberty with normal progression of sexual maturity. The clinical presentations could be Gonadotropin-dependent precocious puberty , Gonadotropin-independent precocious puberty or Incomplete precocious puberty. Gonadotropin-dependent precocious puberty is associated with accelerated linear growth for age, advanced bone ages and increased levels of follicle stimulating hormone ,luteinizing hormone, estradiol, and testosterone. Gonadotropin-independent precocious puberty is associated with suppressed FSH and LH levels and increased oestrogen or testesterone. There are various causes and Hamartoma is one of them.