Oedema is a clinical diagnosis for the collection of fluid in the interstitial spaces. It can range from mild localized pitting to severe generalized swelling called anasarca . The causes are numerous but the most common causes of generalized oedema are: renal (nephrotic and nephritic), cardiac (congestive cardiac failure), nutritional (kwashiorkor), and angioneurotic. Severe oedema can result in blister and ulceration causing local infection.